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In fact, MOTS-c levels naturally rise during exercise, and giving MOTS-c to mice has been shown to enhance their physical performance (they can run longer on a treadmill)

doi:10.1002/jssc.200700404 Metcalfe CD, Chu S, Judt C et al (2010) Antidepressants and their metabolites in municipal wastewater, and downstream exposure in an urban watershed

Values are expressed in mM (K M ), s 1 (k cat ,), mM 1 s 1 (k cat /K M ), and mol

These electrophilic modulators mainly interact with C151 in KEAP1, thereby inhibiting NRF2 ubiquitination and increasing the activity of ARE-mediated antioxidant and detoxifying enzymes [280]