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82 , 83 , 89 , 90 , 92 Among individuals of African ancestry who have one copy of e3 and one of e4, those with a particular variant of e3 called R145C are at increased risk of developing Alzheimer's dementia compared with those who do not have this variant

After adjusting for insulin resistance, the differences in GLP-1 sensitivity between lean and obese subjects were no longer significant, suggesting that its effects are modulated by the individuals insulin sensitivity status

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Furthermore, expression of TJ proteins ZO-1 (Fig