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GLP-1 Receptor Agonists for obesity care Incretin hormones Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted by enteroendocrine L-cells located in the distal small intestine and colon when nutrients are consumed [14, 15]

After adjustment for age, sex, baseline BMI, baseline HbA1c, and hepatosteatosis grade, semaglutide remained independently associated with greater percentage weight loss at 6 months (adjusted = 6.16% points

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