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These honest reviews tell us that, while semaglutide weight loss results may vary for each person, many patients start seeing noticeable changes within the following timelines: Semaglutide may yield consistent results, but the timeline can vary among different patients, as the efficacy of the drug depends on how your body responds to GLP-1s, as well as your lifestyle

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Thats important because it expands the number of people who could benefit from the drug, says Tiffany Powell-Wiley, a cardiologist and epidemiologist at the National Heart, Lung and Blood Institute in Bethesda, Md