The idea is simple instead of continually escalating to higher doses, some patients may achieve meaningful benefits with lower doses, particularly when medication is combined with nutrition, resistance training, sleep optimization, and regular follow-up
GLP-1 exerts anti-inflammatory effects by suppressing the NF-B signaling pathway, which leads to a decrease in the production of pro-inflammatory cytokines like TNF- and IL-6, thereby mitigating liver inflammation and fibrosis
Multidisciplinary support is often beneficial and may include: Dietetic input to establish regular, balanced eating patterns without restrictive dieting Support groups and peer support through organisations like Beat (the UK's eating disorder charity) Treatment of co-occurring conditions such as depression, anxiety, or ADHD Weight management programmes if obesity is present, delivered sensitively to avoid exacerbating disordered eating Access to eating disorder services varies across the UK
The mean (SE) total costs over 2 years were $63 483 ($1563) for GLP-1 RAs and $51 794 ($1724) for MBS ( P .05
