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A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]

The effectivity of BBB-specific cellular internalization and permeability can be increased by the combination of different targeting ligands on the surface of nanocarriers

Biochim Et Biophys Acta (BBA) Proteins Proteom 1804(8):16901694 Wang S, Yuan YH, Chen NH, Wang HB (2019) The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in Parkinsons disease

PMID: 33717590 J Thorac Dis2020 May;12(5):2137-2145