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A 2025 cross-sectional study published in Frontiers in Nutrition (Johnson et al., 2025) found that GLP-1 users frequently consumed protein below the levels associated with lean mass preservation in published weight loss research

Ipamorelin is not approved for human use by the FDA or any regulatory agency

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GLP-1 receptors exist in brain regions involved in mood regulation, prompting questions about whether these medicines might influence anxiety