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In another study, response to escitalopram was associated with higher plasma baseline 5-HT levels, lower baseline KYN/TRP and QA/TRP ratios, and, among remitters, a treatment-related increase in the KYNA/3-HK ratio [193]
739 In the MCAO/R model of rats, the expression of SLC7A11 is downregulated, accompanied by inhibition of GSH and GPX4, suggesting that the deficiency of xCT in cerebral I/R injury may be the main cause of lipid peroxidation and ferroptosis
The open field, RotaRod, and wire hanging tests were employed to assess balance and locomotor activity, while the shuttle box test was utilized to evaluate passive memory
Akkus G, Sert M
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