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(77) showed that overexpression of the rat kidney dicarboxylate carrier in a cell line derived from rat kidney proximal tubules (NRK-52E) increased the mGSH pool size by two- to 10-fold with respect to wild-type NRK-52E cells, thus demonstrating a role for this carrier in the mitochondrial transport of GSH in exchange with inorganic phosphate

However, contradictory findings were reported by Gougeon et al., who biopsied testes from 26 men aged 1680 and found no significant change in LC number with aging [49]

Attempting to split doses by administering partial injections or dividing the contents between multiple injections compromises both the sterility of the medication and the precision of dosing