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Adding supplemental vitamin C in the form of ascorbic acid, the equivalent form of vitamin C found naturally in foods, will increase blood levels further, but natural absorption of vitamin C above the intake of about 200 mg decreases sharply with increasing doses by as much as 50%

Human safety data is limited, and risks may depend on dose, route, sourcing, health history, and other medications

doi: 10.1080/00071668.2016.1237767

J Pineal Res 62:e12379 Li H, He J, Yang X, Li X, Luo D, Wei C, Ma J, Zhang Y, Yang J, Zhang X (2016) Glutathione-dependent induction of local and systemic defense against oxidative stress by exogenous melatonin in cucumber ( Cucumis sativus L)