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For instance, in a placebo-controlled study of 24 obese patients with T2DM, exenatide treatment for 12 weeks exerted an anti-inflammatory effect independent of body weight reduction, as illustrated by reduced circulating levels of various pro-inflammatory mediators such as TNF-, IL-1, IL-6, serum amyloid A, and MMP-9 [79]

Dysautonomia and POTS Symptoms: By repairing damaged small nerve fibers and supporting the overall integrity of the autonomic nervous system, B12 helps normalize the erratic nerve signaling that drives rapid heart rates, blood pooling, and temperature dysregulation in dysautonomia

Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons

MC4R mutations are a rare form of genetic disorder that leads to obesity (Pictured to the right), reduced metabolic rate and glucose imbalances