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Skin Pigmentation & Tanning Melanotan II stimulates MC1R receptors in melanocytes, leading to increased melanin production . Research shows this results in darker skin pigmentation , which has been investigated for treating conditions like vitiligo and photosensitivity disorders . Why it matters: Increased melanin may help protect against UV-induced DNA damage and sunburn

CGRP-positive nerve fibers that innervate the airways originate from the trigeminal, nodose-jugular and dorsal root ganglia [138]

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Participants were randomized to CagriSema, semaglutide 2.4 mg alone, cagrilintide 2.4 mg alone, or placebo