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Both GLP-1 and GLP-2 exert potential anti-inflammatory properties as well as improve glycemic control, nutrient absorption, and stimulate intestinal proliferation

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Compared to traditional addiction treatments, GLP-1RAs offer a novel mechanism by targeting metabolic and neuroendocrine pathways rather than direct neurotransmitter modulation

The predictive accuracy of this risk signature was evaluated using time-dependent receiver operating characteristic (ROC) analysis with the timeROC package, followed by validation in the independent ICGC-HCC cohort