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Moreover, drugs targeting mutant isocitrate dehydrogenase in acute myeloid leukemia (AML) have marked a milestone in precision cancer metabolism therapy, demonstrating the potential effectiveness of metabolic treatment ( Due to its extensive clinical application experience and wide accessibility, traditional Chinese Medicine (TCM) plays a crucial role in cancer treatment in China ( Above all, targeting cancer metabolic abnormalities has been recognized as a promising strategy to remodel the tumor microenvironment and enhance antitumor immune responses