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Accumulating evidence indicates that Chinese herbal compounds, active constituents, and formulated prescriptions can ameliorate ferroptosis in PCOS by remodeling the gut microbiota and modulating ferroptosis-associated pathways (Table 1)

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According to some publications, the extent and the intensity of physiological oral mucosal melanin hyperpigmentation increase with age probably owing to the cumulative effects of endogenous and extrinsic melanogenic stimuli, such as inflammatory processes, drugs, tobacco smoke, and recurrent minor functional injuries [4, 6, 11, 13]

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Cell 86 , 643653 (1996)

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