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A team of researchers developed a nanostructure-based GLP-1R agonist capable of crossing the BBB that significantly attenuated neuroinflammation and memory loss in an A peptide-induced mouse model of AD by inhibiting the inflammatory responses of microglia and astrocytes (Zhao et al., 2022)

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Why Prior Authorization for GLP-1s is Essential (and Its Benefits) Prior authorization (PA) for GLP-1 medications, while an administrative step, serves crucial purposes: ensuring appropriate utilization, managing healthcare costs, and promoting patient safety

The SUSTAIN and PIONEER trial series highlighted not only its effectiveness in these areas but also its cardiovascular safety profile, making it a suitable option for a broad spectrum of patients, including those with a high risk of cardiovascular events