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As a control, GLP-1 (PDB ID: 1D0R) with the GLP-1 receptor docking analyses, and the HSA-binding DARPin (trRosetta predicted structure) with human serum albumin have been conducted

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[4] Cold is most effective at relieving pain and swelling during the first 3 days after the injury, but after that, using heat can help relax the area and may increase circulation, which can promote healing