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You obviously cant use weight loss as your marker. A Novo Nordisk spokesperson told The Post that semaglutide, the active ingredient in Ozempic and Wegovy, has been extensively studied in clinical trials

It doesnt require a sterile compounding environment

When split dosing might make sense Despite the lack of clinical trial data, there are specific situations where split dosing has a reasonable pharmacological rationale and the benefit-risk calculus favors trying it