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Policy The finding, achieved with weekly injections of the GLP-1 receptor agonist semaglutide (Wegovy, Ozempic) in the multicenter SELECT trial, establishes overweight/obesity as a modifiable risk factor for CVD, according to lead investigator A
Recent systematic reviews and meta-analyses on GLP-1RA and mental health outcomes have also shown that the subjects included in the trials, such as obese individuals, patients with type 2 diabetes, and subgroups with mental disorders, have significantly increased baseline depression and suicide risks themselves [29, 46, 47]
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