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Semaglutide is used to regulate blood sugar levels and increase insulin secretion

If your semaglutide has been exposed to heat, the safest approach is to contact your prescribing provider rather than using potentially compromised medication

Signs That Require Urgent Attention Need immediate medical review to prevent complications with: Persistent high-volume watery stools Fainting Rapid heart rate Low urine output Symptoms of severe electrolyte loss Would Diet, Timing, Or Dose Adjustments Help Reduce Diarrhea These factors can reduce GI upset for some people: Slower dose increases Attention to meal composition Staying hydrated Avoiding sudden large meals high in simple sugars Your clinician can advise on dose schedules and whether temporary symptomatic therapy, such as oral rehydration or short-term anti-diarrheal medication, is appropriate

J Biol Chem 272:27002708 Clarke DD, Sokoloff L, Siegel GJ, Agranoff BW, Albers RW, Fisher SK, Uhler MD (1999) Circulation and energy metabolism of the brain