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The ongoing loss of functional genes partly reflects host adaptations that replace functions previously encoded in the symbiont genome 44,47

The essential module of metal homeostasis involves uptake and transport, chelation and sequestration processes

Common injection sites include the abdomen (avoiding the area immediately around the navel), anterior thigh, or upper arm

At the American Diabetes Association's Scientific Sessions, Mass General Brigham researcher Vanita Aroda, MD, presented results from SOLSTICE, a phase 2b randomized, placebo-controlled clinical trial evaluating the oral GLP-1 receptor agonist elecoglipron