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glutamate reuptake, primarily by astrocytes, is extremely efficient (reviewed in Pittenger, Coric et al., 2008), and therefore increased activity of glutamatergic neurons will not necessarily increase tonic concentrations of glutamate in tissue or in CSF

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Poor sleep disrupts the intestinal lining and reduces L-cell activity, while chronic stress elevates cortisol levels, which can suppress GLP-1 signaling

L-carnitine is an amino acid derivative that helps break down fatty acids for energy and fuel for the body