Seek immediate medical care (emergency department or urgent care) if you experience: Severe, persistent abdominal pain, especially in the right upper quadrant, lasting more than a few hours Abdominal pain accompanied by fever (temperature above 100.4F or 38C) Yellowing of the skin or eyes (jaundice) Severe nausea and vomiting preventing fluid intake and leading to dehydration Dark urine combined with pale stools Abdominal pain radiating to the back, which could indicate pancreatitis The combination of fever, jaundice, and abdominal pain, which may indicate cholangitis (bile duct infection) Confusion, extreme weakness, or very low blood pressure with any of the above symptoms (possible signs of sepsis) Important: If you experience severe, persistent abdominal pain with or without vomiting that could be consistent with pancreatitis, stop taking semaglutide immediately and seek urgent medical care, as directed in the FDA labeling
Semaglutide is administered once a week as a subcutaneous injection, taken on the same day at the same time each week
Medically reviewed by: Jayden Lee, PharmD, EMBA Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes
Semaglutide and other drugs in its class have been life-changing for people living with obesity around the world
