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Apart from the beneficial effects and detrimental side effects of melanin production, melanocytes can also protect against microbial infections by acting as antigen-presenting cells producing cytokines, phagocytosing microorganisms, and degrading both phagocytosed bacteria and bacteria in the microenvironment by means of melanosomal lysosomal enzymes [4, 6, 7]
The gene responsible for type 4 Bartter syndrome encodes the common accessory -subunit of the voltage-gated Cl channels identified as ClC-Ka and ClC-Kb (the CLCNK channels)
10.3389/fpls.2015.00831 5 BaligaS.MuglikarS.KaleR
In addition, cancer cells themselves have unique characteristics to form vessel-like channels within the tumor in a process known as vascular mimicry (Ruoslahti, 2002)
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