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Additionally, the class Malasseziomycetes was enriched in CRC patients, while the classes Saccharomycetes and Pneumocystidomycetes were found to be depleted in the CRC group ( Streptococcus bovis ( S

GDMT for HFrEF typically includes evidence-based beta-blockers, angiotensin receptor neprilysin inhibitors (ARNIs), angiotensin receptor blockers (ARBs), angiotensin-converting enzyme (ACE) inhibitors, mineralocorticoid receptor antagonists (MRA), and sodium-glucose cotransporter 2 inhibitors (SGLT2is), particularly in patients with obesity or T2DM [53]

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