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You should not take Contrave if you: have uncontrolled high blood pressure have or have had seizures or an eating disorder like anorexia or bulimia are currently using opioid pain medications or are in opioid withdrawal take other medicines containing bupropion drink a lot of alcohol and suddenly stop have taken a monoamine oxidase inhibitor (MAOI) in the last 14 days You should use caution with Wegovy if you: have had problems with your pancreas or kidneys have type 2 diabetes and a history of diabetic retinopathy are taking insulin or other diabetes medications, as Wegovy can increase the risk of low blood sugar (hypoglycemia) Pregnancy and breastfeeding Neither drug is recommended during pregnancy, as weight loss offers no benefit to the fetus and may cause harm

Temperature control is the primary factor that determines how long your compounded semaglutide remains safe to inject

If syncope causes a fall or head injury, urgent medical assessment is required

Both Ozempic and the generic semaglutide products are approved by Health Canada for management of diabetes, but for years doctors prescribed it off-label for weight loss before manufacturer Novo Nordisk began selling Wegovy in Canada in 2024