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Neuropsychopharmacology 48 , 351361 (2023)

Variations in FTO and MC4R genes also influence appetite regulation and satiety, which indirectly affects gastric dynamics

For weight loss, the NHS offers a similar medication, Wegovy , but under strict eligibility criteria

This analysis concludes that while GLP-1 agonists demonstrate significant promise, their ultimate impact depends on addressing cost, accessibility, and long-term sustainability concerns