To align costs and evidence, CVS standard template formularies (as of Feb 2024) made Wegovy and Saxenda its preferred agents among GLP-1s for obesity, relegating other anti-obesity drugs (Qsymia, orlistat, phentermine, etc.) to lower tiers ( [41] )
The American Journal of Medicine , 138 (6), 934-940
There have been suggestions recently that GLP-1RAs could help treat these conditions, but it was the consistency that was surprising the same positive effect was seen across tobacco, cannabis, opioids, and alcohol
Additionally, the diabetic kidney has increased oxygen demand due to increased sodium reabsorption and (single-nephron) hyperfiltration via increased Na + , K + ATPase activity at the basolateral surface of the tubules [13]