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Adalimumab Adalimumab (Humira) is a biological, fully human, recombinant immunoglobulin G (IgG) anti-TNF monoclonal antibody (mAb) with high affinity, used for the treatment of numerous autoimmune and inflammatory disease conditions, including rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, Crohn's disease, and ulcerative colitis

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A small clinical study in healthy volunteers shows that pretreatment with quercetin increases plasma levels and prolongs the half-life of a single dose of cyclosporine (Neoral, Sandimmune), a substrate of CYP3A4

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