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Introducing these non-natural amino acids into the peptide sequence, particularly at the proteolysis site, is an effective strategy for extending the plasma half-life of peptide drugs

Functional peptide-based drug delivery systems

However, hormonal therapy may cause side effects such as weight gain, depression, acne, body hair, and irregular bleeding

Comparative analysis of deregulated pathways in our high and low ADA metabolomic datasets with high and low ADA expressing transcriptomics data of RA patients To further validate our metabolomics data of High ADA and Low ADA RA patients, we compared their metabolomic pathways with the high ADA expressing PBMCs (GSE15573) and low ADA expressing synovial macrophages (GSE97779 and GSE10500) GEO datasets