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However, levothyroxine should be taken on an empty stomach 3060 minutes before breakfast for optimal absorption, whilst metformin is typically taken with or after meals to reduce gastrointestinal side effects
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A 2023 meta-analysis of 11 clinical trials found that GLP1 RAs significantly improved natural pregnancy rates and menstrual regularity in women with PCOS - while also reducing insulin resistance, testosterone levels, and BMI [Source: BMC Endocrine Disorders, 2023] When insulin resistance and excess weight are brought under control, hormonal balance often follows