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In another study, an 84-week open-label trial with about 800 participants, people taking CagriSema had an average of 23% weight loss versus about 25 to 26% for tirzepatide (Zepbound) at the highest dose

As expected, ingestion of the mixed meal in nonsurgical controls resulted in decreased abundance of multiple lipid species and increased abundance of AAs at 30 minutes, with return to baseline at 120 minutes