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Discussion Combining experimentally determined GLP-1R structures with structurefunction studies and simulations of receptor dynamics provides unique insights into how distinct agonists engage and activate the receptor
72 (Suppl.), 152663(2025)
Studied in models involving melanocortin receptor signaling and pigmentation-related biological pathways
In addition, consistent with the findings reported elsewhere, we found DMF induces the activation of NRF2, and NRF2 targets such as those involved in cystine uptake (SLC7A11) and GSH biosynthesis (GCLM and GCLC, the mediator and catalytic subunits of GCL) (Fig
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