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9 Nrf2 is usually locked in the cytoplasm, but activation by DMF/MMF allows it to translocate to the nucleus where it activates a pathway of genes involved in antioxidant responses, detoxification, and the activity of cytoprotective anti-inflammatory factors

Majority of AA in plant cells is the result of Smirnoff-Wheeler pathway, catalyzed by L-galactano--lactone dehydrogenase in the plant mitochondria, with the remaining being generated from D-galacturonic acid