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Every constituent cell of the NVU contributes to the BBBs integrity, and any dysfunction might result in the barrier breakdown, with dramatic consequences such as neuroinflammation and neurodegeneration (Kempuraj et al., 2016

However, its important to note that theres only a proven benefit to taking vitamin B12 for folks who have a deficiency that is causing anemia

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Prolactin and prostate hypertrophy: a pilot observational, prospective, case-control study in men with prolactinoma