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The actual result should fall within the specification range

This crucial issue has been investigated by techniques such as microneurography, which allows recording directly spontaneous efferent activity of post-ganglionic SNS fibers controlling muscle vascular tone (Vallbo et al., 2004), and regional NE spillover, which is crucial in order to investigate organs like heart and kidney, whose efferent nerve traffic is not directly recordable in humans

We use experimentally determined forms for these allosteric interactions but sometimes the details of the kinetics are not known, forcing us to make reasonable educated guesses

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