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ESSENCE Semaglutide in MASH

Many biological drugs, especially JAK1 inhibitor UPT, have been put into clinical use due to their good therapeutic efficacy and safety

1Model based estimates based on an analysis of covariance model including treatment and type 2 diabetes status as factors and baseline value as a covariate 2Not included in the pre-specified hierarchical testing 3Model based estimates based on a mixed model for repeated measures including treatment and type 2 diabetes status as factors and baseline values as a covariate 4Baseline value is the geometric mean Overview of Clinical Trial in Pediatric Patients WEGOVY was evaluated in a 68-week, double-blind, randomized, parallel group, placebo-controlled, multi-center trial in 201 pubertal pediatric patients aged 12 years and older with BMI corresponding to 95th percentile standardized for age and sex (Study 7) (NCT#04102189)

This dual action leads to greater appetite suppression and improved metabolic control