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Given the poor history and elevated acetaminophen level, treatment based on the Rumack-Matthew nomogram (Figure 1) was felt to be beneficial

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However, Cagrilintide failed to induce significant cFos activation in RAMP1/3 KO mice, whereas sCT retained its ability to do so, likely via residual AMY2R signaling

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Hardan AY, Fung LK, Libove RA, et al

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