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Description

Results Both metformin and GLP-1 RA therapy individually lowered the risk of adiposity-related cancers and mortality compared with DPP4 inhibitors

This also makes dose optimisation easier for the treating doctor

Outcomes In the overall analysis, the risk of MACE was reduced by 14% (HR = 0.86, 95% CI, 0.790.94, P = 0.006) compared with placebo with no significant heterogeneity between trials (I 2 = 50.0%, P = 0.08) (Fig