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Although localized intratumoral delivery of CD133-targeted CAR-T cells has been proposed as a strategy to mitigate this risk, clinical experience remains extremely limited, with only one study to date reporting its application in patient-derived GBM stem cells

doi: 10.1093/eurheartj/ehy799 89 WangQ.GuoM.LiuY.XuM.ShiL.LiX.et al

Though fast-acting, intravenous glutathione is linked with severe safety effects such as anaphylaxis and hepatotoxicity, which are further worsened by the absence of standard dosing guidelines

Treatment The treatment for L Carnitine deficiency typically involves L Carnitine supplementation and addressing any underlying causes that may contribute to the deficit