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Modulation of CPT-1 may affect energy metabolism and food intake, and research is ongoing into the effects of both stimulation and inhibition of CPT-1 and in relation to obesity management [74]

GLP-1 agonists (GLP-1s) and GLP-1/GIP agonists are a group of medicines that boost the actions of hormones we already make in our body called incretin hormones

Novo Nordisk plans to file for regulatory approval in the U.S

Moreover, taking into account numerous clinical studies and experimental data showing that the pathogenesis of depression is not limited to the brain, but may also result from an impaired cross-talk between the central nervous system and other systems in the body, particularly the immune, endocrine and digestive systems, therapeutic GLP-1 analogs such as exendin-4 or liraglutide can also normalize their functioning in many cases, thus preventing the occurrence of maladaptive brain changes associated with depressive symptoms