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In the dermato-aesthetic field, cycles of GSH IV combined with vitamin C show results on skin tone and reduction of hyperpigmentation, albeit in the absence of formal dedicated RCTs. Protocols and outcome assessment Currently used protocols for NAD IV involve doses of 250-500 mg per session, with slow infusions (2-6 hours) and weekly frequency for 4-8 weeks, followed by monthly maintenance

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Once a follicle has been producing non-pigmented (white) hair for years, the melanocyte reservoir is often depleted, making full reversal unlikely

People who start with a high dose may experience some mild nausea