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Tendon and Ligament Repair Moderate to Strong Evidence Evidence Rating: Moderate-Strong (Several animal studies, some independent replication) Research support for musculoskeletal healing is substantial: Achilles tendon injuries Ligament damage (MCL, ACL) Rotator cuff healing General tendinopathy Surgical repair enhancement The FAK-paxillin mechanism and VEGF upregulation provide clear biological rationale for these effects

Vitamin B12, in particular, is a co-factor in myelin formation

The tissue repair and anti-inflammatory mechanisms proposed for BPC-157 and PDA are traceable to measurable biological markers

Other studies have noted potential benefits for improving mobility, strength, and flexibility in joints and connective tissue