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Mechanistically, metformin exerts its anti-tumor effects primarily through two pathways: first, by improving insulin resistance, thereby reducing circulating insulin and IGF-1 levels, it indirectly inhibits tumor growth

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Many studies confirm the correlation between exposure to chronic stress and the occurrence of oxidative stress and elevated markers of oxidative stress ( Studies using animals show that the long-term effects of cortisol can affect individual markers of oxidative stress (9294)