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4.3 Neuroinflammation and immune signaling interference Beyond supporting energy metabolism, FAD and FMN critically modulate neuroinflammatory pathways by influencing signaling cascades such as TNFR1/NF-B, MAPK, and PI3K-Akt

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Feverfew inhibits the production of several inflammatory mediators that may be involved in migraine onset, suggesting it may be promising in managing migraine attacks