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Similarly, in LPS-stimulated HaCaT model, nepetin has been shown to attenuate ROS accumulation and reduce the production of inflammatory cytokine, potentially through modulation of the MyD88-MKK3/6AktNF-B signaling pathway (Gong et al., 2024)
Sleep disruption increasingly common in midlife adults significantly blunts this pulse
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In mammalian nervous systems, many different types of chemical substances, including amino acids (e.g., glutamate), monoamines (e.g., dopamine, norepinephrine), acetylcholine, peptides (e.g., substance P), serve as neurotransmitters to bind their corresponding receptors, then activate ion channels, and consequently produce ion flux 1 , thereby inducing membrane potential changes that lead to signal propagation for neurotransmission 1,2,3,4
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