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This is often the case with people with disorders such as IBS or inflammatory bowel diseases (Crohns / ulcerative colitis) or those who have undergone weight loss surgery

This is because having a higher body weight, especially weight carried around the middle, can lead to insulin becoming less effective and being produced in smaller quantities

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H., et al., GlucagonLike Peptide 1 Receptor Agonists and Risk of Thyroid Cancer: An International Multisite Cohort Study, Thyroid 35 (2025): 6978