novo nordisk oral glp-1 launched an version of its injectable to US markets on Jan 5 What's next for GLP-1 innovation:

What employers need to know about the new oral GLP-1 Wegovy The treatment of obesity and cardiometabolic-related conditions has been transformed by GLP-1 medications, and new developments in this rapidly evolving market tend to make headlines

doi: 10.1055/s-2008-1040482

While a decrease in serum urea level and an increase in serum creatinine level were detected in the MTX group, WPC administration reversed these results up to control group levels

So this is why the retooling of the GLP-1 hormone is why Ozempic and similar injectables are taken weekly, because the chemical at the core of it all, semaglutide, has a half life of a week