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We can see from the prescribing documentation for Wegovy that there were at least three randomized, double-blind, placebo-controlled trials with adults for this medication
Confounding by concomitant diabetes therapies (especially SGLT2 inhibitors) is substantial in real-world datasets and must be explicitly controlled in any causality analysis
The primary objective of the phase 3b SOUL trial was to evaluate the effects of oral semaglutide 14 mg, in addition to standard of care, on reducing the risk of MACE in adults with type 2 diabetes at high risk for major cardiovascular events
If a connection is confirmed, it may apply to other drugs in the same class
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