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However, early-stage potency loss (5 to 20%) is invisible

As the risk of ESRD imposed by RA is relatively higher in relatively young individuals not suffering from any other medical conditions, such as obesity, DM, HTN, DL, and CKD, kidney-protective treatment, such as biologic agents, should be preferentially considered among these patients with RA

Mechanism of lipoic acid in the treatment of metabolic dysfunction-associated steatotic liver disease In preclinical studies, LA has been shown to improve nonalcoholic fatty liver disease by modulating a variety of molecular pathways

doi: 10.1016/j.pnpbp.2005.03.015 76 LeonardBE